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DNA Synthesis. How do DNA synthesis actually works?

Learn how DNA synthesis work. The best machines for synthesizing DNA. The CRISPR, Talens genome editing tools.

So what are the best tools for genome Editing, and the best machines for DNA synthesis?

So how DNA Synthesis actually works?

DNA biosynthesis occurs when a cell divides, in a process called replication. It involves separation of the DNA double helix and subsequent synthesis of complementary DNA strand, using the parent DNA chain as a template.[1]

DNA synthesis is the biological process by which a deoxyribonucleic acid (DNA) molecule is created. In the cell, each of the two strands of the DNA molecule acts as a template for the synthesis of a complementary strand.[2]

So are they machines that make DNA synthesis?

Gene synthesis machines: DNA chemistry and its uses

Deoxyoligonucleotides can now be synthesized rapidly and in high yield because of recent advances in nucleic acid chemistry[3]

So are there actually methods or real GMO’s that were created and thrive?

Genome Editing Tools
Genome Editing Tools Source Youtube

What are some new discovered genome editing tools?

  • Zinc Finger Nucleases.
  • Talens
  • CRISPR/Cas9

TALEN and CRISPR/Cas Genome Editing Systems: Tools of Discovery

The rapid evolving of genetic engineering allow to make DNA synthesis in powerful machines. Genetic Engineering actually emerged in with Paul Berg in 1972 in a new way: recombinant DNA.

So what is CRIPSR/Cas9?

CRISPR is a powerful and natural easy to use tool for editing genomes. CRISPR technology was adapted from the natural defenses mechanisms of bacteria and archae.

and what is Talens?

TALENs: a widely applicable technology for targeted genome editing

Talens is acronym for transcription activator-like effector nucleases. So these targetable nucleases are used to induce double-strand breaks (DSBs).

So how to learn DNA topics and genetics?

By the way a good way to learn science is by doing science divulgation. By creating a blog and writing about science. Curating articles. This is important if you want to make genetics. Become a fan of geneticists and researchers.

Conclusions

So for DNA synthesis a genome editing tool is required, and a machine for synthesizing DNA in vitro.

DNA SYNTHESIZERS MACHINES
DNA SYNTHESIZERS MACHINES

References

[1] The Genetic Information (I). (2017, January 1). ScienceDirect. https://www.sciencedirect.com/science/article/pii/B9780128035504000215

[2] Tracking break-induced replication shows that it stalls at roadblocks. (2021, January 20). Nature. https://www.nature.com/subjects/dna-synthesis?error=cookies_not_supported&code=c4574ec6-1dac-40a1-ad87-b46e42e18ce5#:%7E:text=DNA%20synthesis%20is%20the%20biological,synthesis%20of%20a%20complementary%20strand.

[3]Caruthers, M. H. (1985, October 18). Gene synthesis machines: DNA chemistry and its uses. Science. https://science.sciencemag.org/content/230/4723/281

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Genome Editing with CRISPR-Cas9

Genome Editing CRISPR/Cas9

CRISPR will rise like never before, genetic engineering is a scientific reality and will make humanity rise, again!

This animation depicts the CRISPR-Cas9 method for genome editing – a powerful new technology with many applications in biomedical research, including the potential to treat human genetic disease. Feng Zhang, a leader in the development of this technology, is a faculty member at MIT, an investigator at the McGovern Institute for Brain Research, and a core member of the Broad Institute. Further information can be found on Prof. Zhang’s website at http://zlab.mit.edu .